Top 25 College Hoops Picks Against the Spread – Sunday, February 23

Published 7:09 pm Saturday, February 22, 2025

Sunday’s college basketball slate includes three games featuring a ranked team in action. Among those games is the UConn Huskies playing the St. John’s Red Storm. Continue reading for ATS picks for each matchup.

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AP Top 25 Picks ATS Today

No. 10 St. John’s Red Storm vs. UConn Huskies

Spread Prediction

  • Computer Prediction: St. John’s 77, UConn 68
  • Projected Favorite: St. John’s by 9.2 points
  • Pick ATS: St. John’s (-4.5)

Bet on the St. John’s-UConn spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 12 p.m. ET
  • Location: New York City, New York
  • Venue: Madison Square Garden
  • TV Channel: FOX
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Indiana Hoosiers vs. No. 13 Purdue Boilermakers

Spread Prediction

  • Computer Prediction: Purdue 77, Indiana 72
  • Projected Favorite: Purdue by 4.8 points
  • Pick ATS: Purdue (-4.5)

Bet on the Indiana-Purdue spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 1:30 p.m. ET
  • Location: Bloomington, Indiana
  • Venue: Simon Skjodt Assembly Hall
  • TV Channel: CBS
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 22 Memphis Tigers vs. Florida Atlantic Owls

Spread Prediction

  • Computer Prediction: Memphis 83, Florida Atlantic 72
  • Projected Favorite: Memphis by 10.8 points
  • Pick ATS: Memphis (-9.5)

Bet on the Memphis-Florida Atlantic spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 2 p.m. ET
  • Location: Memphis, Tennessee
  • Venue: FedExForum
  • TV Channel: ESPN2
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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